Selasa, 29 Maret 2011

[U316.Ebook] Get Free Ebook Logic Synthesis, by Srinivas Devadas, Abhijit Ghosh, Kurt Keutzer

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Logic Synthesis, by Srinivas Devadas, Abhijit Ghosh, Kurt Keutzer

Logic synthesis enables VSLI designers to rapidly lay out the millions of transistors and interconnecting wires that form the circuitry on modern chips, without having to plot each individual logic circuit. This guide to logic synthesis techniques spotlights not only the synthesis of two-level, multi-level and combinational circuits, but also their testability.

  • Sales Rank: #1865534 in Books
  • Published on: 1994-06-01
  • Ingredients: Example Ingredients
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.30" h x 1.19" w x 6.30" l,
  • Binding: Hardcover
  • 448 pages

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0 of 0 people found the following review helpful.
textbook
By J. Lacoste
matched description well, i would buy again. . . . . . . . . . . . . . .

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Minggu, 27 Maret 2011

[D978.Ebook] Ebook The Sayings Of Confucius, by Leonard A. Lyall

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The Sayings Of Confucius, by Leonard A. Lyall

Leopold Classic Library is delighted to publish this classic book as part of our extensive collection. As part of our on-going commitment to delivering value to the reader, we have also provided you with a link to a website, where you may download a digital version of this work for free. Many of the books in our collection have been out of print for decades, and therefore have not been accessible to the general public. Whilst the books in this collection have not been hand curated, an aim of our publishing program is to facilitate rapid access to this vast reservoir of literature. As a result of this book being first published many decades ago, it may have occasional imperfections. These imperfections may include poor picture quality, blurred or missing text. While some of these imperfections may have appeared in the original work, others may have resulted from the scanning process that has been applied. However, our view is that this is a significant literary work, which deserves to be brought back into print after many decades. While some publishers have applied optical character recognition (OCR), this approach has its own drawbacks, which include formatting errors, misspelt words, or the presence of inappropriate characters. Our philosophy has been guided by a desire to provide the reader with an experience that is as close as possible to ownership of the original work. We hope that you will enjoy this wonderful classic book, and that the occasional imperfection that it might contain will not detract from the experience.

  • Published on: 2015-07-24
  • Released on: 2015-07-24
  • Original language: English
  • Dimensions: 9.00" h x .26" w x 6.00" l,
  • Binding: Paperback
  • 114 pages

About the Author

Burton Watson has taught at Columbia, Stanford, and Kyoto Universities and is one of the world's best-known translators of Chinese and Japanese works. His translations include The Tales of the Heike; The Lotus Sutra; the writings of Zhuangzi, Mozi, Xunzi, and Han Feizi; The Columbia Book of Chinese Poetry; and Records of the Grand Historian.

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25 of 25 people found the following review helpful.
confucius
By aunted
I am still reading this book on my kindle and find it every intersting. I have heard the "Confucius said" all my life but never really knew much about him. This book tells about his life, his students and the things the Master taught his students. I would recomend it for all who are interrested in the religion he taught as well as his belief.

41 of 46 people found the following review helpful.
Not current fashion, but...
By Hal O'Brien
This is the translation by Leonard A. Lyall, from 1909. As such, it uses the older Wade-Giles romanization. I prefer Ames & Rosemont from more recent translations, but this is very representative of its turn-of-the-20th-century type.

9 of 10 people found the following review helpful.
Ancient wisdom
By Israel Drazin
The truth, scholars emphasize, is the truth, no matter what its source, even if the speaker is of a different race, religion, sex, or culture. This being true, people should pay attention to The Sayings of Confucius.

Confucius was born in 550 BCE. The Jesuits who carried his teachings to Europe called him Confucius, although his name was K'ung Fu-tzu. This book's introduction describes his turbulent time and the people and rulers of the period. It was a time when the country was broken into independent empires, each virtually powerless. Confucius held some government positions, but spent his later years in study and teaching, and gained many disciples. He studied history with the hope that he could find a way to help his people and country, and wrote books called Book of History and Spring and Autumn, and edited Book of Poetry. He died in 479 BCE at age 71.

Confucius did not write The Sayings of Confucius. Some scholars think that it was composed by a disciple of his based on what his teacher actually said. However, there are passages that speak of events long after his death. The general consensus is that the book was composed by students or admirers around 400 BCE. The following are a sample of sayings:

* Smooth words and fawning looks are seldom found with love.
* Put faithfulness and truth first; have no friends unlike thyself; be not ashamed to mend thy ways.
* A gentleman that does not seek to eat his fill...may be said to love learning.
* Not to be known is no sorrow. My sorrow is not knowing men.
* A gentleman puts words into action first, and follows them with words.
* Learning without thought is naught; thought without learning is dangerous.
* To know what we know, and know what we do not know, is wisdom.

Not all of the sayings are wise; some are trite. There is some repetition of thoughts told with different words. Some thoughts are difficult to understand. But these facts should not stop people from reading the book and gainig new ideas.

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Sabtu, 26 Maret 2011

[A105.Ebook] PDF Ebook Appetite For Dysfunction: A Cautionary Tale, by Vicky L Hamilton

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Appetite For Dysfunction is a self-exploratory journey through Vicky’s life. A small town girl who risks everything by dropping out of art school, leaving behind the safety of loved ones and small town values, and making her way to Hollywood. When Vicky arrived, she landed a job as a mere record store clerk, to then miraculously find herself deep in the trenches of an unscrupulous, male dominated, music entertainment business, and blossomed into Hollywood’s most controversial A&R woman and band manager. Vicky followed her dream and achieved it. She became the top female record company executive and personal band manager. Only to reach her aspirations while working with Guns N’ Roses, to then take on the most coveted A&R position to date at Geffen Records, under David Geffen himself. It was common knowledge, that while David Geffen was relaxing at his Malibu beach house, Hamilton was busy scouring dark clubs for talent. Doing the kind of legwork many larger record labels had gotten away from.

Appetite For Dysfunction is the first time Vicky candidly speaks out about the life she lived on the front lines, deep in the heartless world of the music business. Hamilton brings to this book her unbiased observations and shrewd glimpses about who these rock stars and executives are at the core of their beings, and about herself, as well. She expresses her gratitude for her historic past and her accomplishments, as well as her own shortcomings along the way. She shares her victories, her mistakes, the horror stories, and her dark comedic approach to “making it” in the entertainment business. Even while getting her heart broken on many occasions, leading to some cataclysmic breakdowns,Vicky battles to hang on to her integrity. Painfully taking the highroad, as she loses her job at Capitol Records, while facing eviction and a phone that suddenly stopped ringing, Vicky holds her head high, humbly reinvents herself, and literally, goes on with the show.

One of the many highlights of this book is when Vicky produced and released June Carter-Cash’s record, Press On>. Hamilton was so determined to get June a record deal that, when no one else wanted to make a record with June, Vicky started her own label, Small Hairy Dog. Through her relationship with Carter-Cash, while making Press On>, Vicky found herself trusting her own faith and intuition and began questioning her personal lifestyle choices and stopped looking outside of herself for happiness. No longer coming from a place of fear, Vicky finds sobriety and a new perspective on life. Vicky’s persistence and shift of faith paid off when June’s record won a Grammy.

This book is about a small town girl who follows her heart to Hollywood, finds success only to lose it all, after chasing a dream that becomes a nightmare, because nothing and no one are what they appear to be. Hitting the bottom of a dark and lonely abyss to then climb out triumphantly. This book shares Vicky Hamilton’s undeniable optimism, hope and faith-eternal, and is a must read for anyone who is a music fan and curious about the golden era of the record business, and for anyone with a dream of their own.

Vicky Hamilton is a long time Grammy Award-Winning music industry executive and personal manager, featured on VH-1s, Biography Channel's and BBC. 

She is considered one of the most successful female music executives in the industry. Pull down the safety bar, Appetite For Dysfunction is a wild and exhilarating ride.

  • Sales Rank: #1000210 in Books
  • Published on: 2016-02-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.02" h x .80" w x 5.98" l, 1.16 pounds
  • Binding: Paperback
  • 360 pages

Most helpful customer reviews

2 of 2 people found the following review helpful.
I was just going to flip through it and read "the goods" she had on the acts like Motley, Stryper
By fletch gorman
A definitive read for any music lover of the 80's glam metal scene. Initially, I was just going to flip through it and read "the goods" she had on the acts like Motley, Stryper, Poison and GNR, but then I became enthralled at her humble beginnings, her stories of working at records stores and as a cocktail waitress in Hollywood and her (lack of) business acumen and money to support and manage these bands solely on a handshake and her firm belief they had "what it takes" to make it. She doesn't hold back. She "names names". She slams the assholes and schmucks, yet praises those with honesty, integrity and genuineness. Most captivating, is her insight and description of learning about, managing and eventually living with Axl Rose's Bi-Polar Disorder. This book will take you on a captivating, whirlwind ride of sex, drugs and rock-n-roll. The title of her book encapsulates it all, "Appetite for Dysfunction"; and Vicky Hamilton takes you to an all-you-can-eat-buffet, where you leave stuffed and satisfied.

1 of 1 people found the following review helpful.
Salacious stories are few and far between
By Aaron Small
The title and cover art are purposefully meant to attract the attention of Guns N’ Roses fans – and that’s exactly how the book begins. It’s 1986, with author Vicky Hamilton attempting to get the unruly Axl Rose, Slash, Duff McKagan, Izzy Stradlin and Steven Adler over to the Geffen Records offices to sign their deal, as she was the band’s manager. Interest piqued? Well it’s about to be put on hold as the next several chapters go back to Vicky’s “Hillbilly Roots” in West Virginia and Indiana. At age 21, Hamilton moves to Los Angeles and reader interest is renewed when she gets hired on as a management consultant for M�tley Cr�e – a job without pay. After being replaced by Doc McGhee and Doug Thaler, Hamilton went on to work with Stryper, Poison and eventually Guns N’ Roses. At one point the whole band was living in her apartment; yet salacious stories are few and far between. That being said, a $1,000,000 lawsuit was the end result.

Landing a highly coveted A&R position with Geffen, Hamilton has brief liaisons with Faster Pussycat, Enuff Z’Nuff and Salty Dog. By this point Vicky “stayed stoned morning, noon and night;” her love affair with marijuana front and center. After a successful stint with Capitol Records, Hamilton hits “financial and emotional bottom.” Turning to dog-walking as a way to make money, Vicky finds sobriety – along with yoga, prayer and meditation. Those looking for the dirt (pun intended) won’t find much of it within these pages. Despite being a significant player in the ‘80s era of excess, Hamilton’s book is much more about her personal highs and lows, as opposed to the opulent decadence surrounding the bands she guided through the Sunset Strip.

1 of 1 people found the following review helpful.
WHAT A RIDE!!!
By Sue
Having been along for some of this ride, I can tell you it is a blast to read and relive the moments! All that Vicky has seen and done will amaze all readers. It's wonderfully written with truth and humor. I cannot recommend this book highly enough. If you love rock music and want a real inside peek at what went down for Vicky, this is the best read possible!!

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Minggu, 20 Maret 2011

[S558.Ebook] Ebook Download Orbital Mechanics: Theory and Applications 1st edition

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  • Published on: 1600
  • Binding: Hardcover

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Kamis, 17 Maret 2011

[F668.Ebook] Download Queen of Tomorrow (Stolen Empire Book 2), by Sherry D. Ficklin

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Queen of Tomorrow (Stolen Empire Book 2), by Sherry D. Ficklin

Sophie—now Catherine, Grand Duchess of Russia—had a tough first year at Imperial Court. Married at sixteen to Grand Duke Peter, heir to the throne, and settled in their own palace, things start to look up. As a new day dawns, Catherine thinks only of securing her future, and the future of their country, during one of the greatest political upheavals of her time. Fighting desperately against forces that try to depose the Empress Elizabeth and put the young Prince Ivan on her throne, Catherine soon finds herself in the middle of a war brewing between her beloved Prussia and her new empire. While navigating the fragile political landscape, she quickly realizes that she has only begun to discover the tangled web of deceit and infidelity woven over the lavish court of Oranienbaum Palace.

When a strange and delicate alliance forms between the young couple, Catherine glimpses a future of happiness, only to see it vanish at the hands of those who still seek to end her life—and prevent her reign. Out of favor with the empress and running out of options, Catherine must sacrifice her own innocence on the altar of Russia if she is to save the nation and herself. To survive, she will have to do the unthinkable, betray those closest to her and become something greater and more dangerous than she ever imagined she could be… a queen.

  • Sales Rank: #32879 in eBooks
  • Published on: 2015-07-04
  • Released on: 2015-07-04
  • Format: Kindle eBook

From School Library Journal
Gr 9 Up—This sequel to Queen of Someday (Clean Teen, 2014) is a breezy romance with a thick historical veneer. The author clearly states that she plays fast and loose with historical details and dates. This allows readers to be swept along by the story and not be bothered by the accuracy of events or dates. Grand Duchess Catherine of Russia—the future Catherine the Great—has come a long way since her days as a minor Prussian princess. At the Russian royal court, she must navigate the complexities of court life to keep her hopes of ruling Russia alive. She falls in and out of favor with the empress, who treats Catherine as a pawn useful only for producing an heir. Her marriage to Grand Duke Peter is a sham, mostly due to Peter's completely reprehensible behavior. He is childish and mercurial, which endears him to no one. Catherine comes across as intelligent, brave, and resilient, despite her cruel circumstances. She often sees herself sacrificing personal character for the greater good of Russia. The story moves quickly, and the characters use modern, casual dialogue. Because the author is so straightforward regarding her use of authorial license, historical details blur together. Ficklin does stay true to the large sexual appetites of her historical figures—there are a great number of sexual situations. VERDICT Queen of Tomorrow should please many romance lovers and fans of the TV show, Reign, but avid historical fiction readers will find it disappointing.—Lisa Crandall, formerly at the Capital Area District Library, Holt, MI

Review
Praise for Queen of Someday:

"A must-read romance."
~USA Today

"(We) want to read this book for a third time--yes, it's that good."
~Just Jared Jr. Book Club

"If I could rate this book more than five stars, I would. It was INCREDIBLE."
~Kelli from Beautiful Book Chaos

"I don't know when the next book will be out but I can guarantee it will be too long."
~Michelle (Goodreads reviewer)

"(This) book is utterly brilliant."
~Pearl from Bibliopearl Reviews

"Ficklin's writing is a marvel to read."
~Sara from Smitten Over Books

"Queen of Someday is a bright new addition to the YA scene..."
~Bobbi (Goodreads Reviewer)

"...holy crap I loved that ending. It was perfect!"
~Eileen Lee of Book Captain Reviews

About the Author

Sherry is a full time writer from Colorado where she lives with her husband, four kids, two dogs, and a fluctuating number of chickens and house guests. A former military brat, she loves to travel, eat exotic food, and meet new people. She can often be found browsing her local bookstore with a large white hot chocolate in one hand and a towering stack of books in the other. That is, unless she's on deadline at which time she, like the Loch Ness monster, is often only seen in blurry photographs.

Most helpful customer reviews

2 of 2 people found the following review helpful.
Even Better Than The First
By Laura Hernandez
The story just gets better and better and I loved this book even more than the first as it takes us further into the future as Catherine is now married to Peter and we witness more of her suffering. I was immediately swept away by the intrigue and romance. Well written plot with superbly developed characters that seem larger than life. I cannot wait to get ensnared in the third book. I highly recommend this author's books.

2 of 2 people found the following review helpful.
Unlike other trilogies, this is a strong middle entry and a quite enjoyable read (4 stars)
By norcalgal
"Queen of Tomorrow" did not disappoint. For me, the second novel in a trilogy is usually where a series comes to die, but this book equaled, indeed surpassed "Queen of Someday" in terms of plot, storytelling and character.

The pace was quick and breezy, just as the first novel was, with dialogue for today's audience. No formal, stilted language of Imperial Russia here. The characters were consistent from one book to another. The plot was full of the court intrigue we first came to know in QoS, and the best parts for me, were how Catherine deftly, and intelligently is able to navigate the tricky (and potentially deadly) machinations of court life.

There were only two things that gave me pause: first, so some random guy shows up, pledges his loyalty to you above all else, and boom - he's now your personal bodyguard? Is it really that easy? Don't get me wrong, I liked Grigori just fine, but had to give this the side eye.

The second part of the novel that didn't work for me was (SPOILER) the dropped storyline of trying to find out who pushed Catherine down the stairs, resulting in her miscarriage. Both she and Peter seemed so determined to root out the devil who caused the loss of the precious heir to the throne, then nothing...Catherine suspects Elizabetta as the culprit but doesn't seem to do anything to find out the truth, besides rouse the feelings of her countrymen/women at a dinner so as to get their passive help in finding out who done the deed. END SPOILER

But I cannot lie - my favorite parts of the novel involve Catherine and Sergei. I shipped them in the first novel and am so very glad to see their relationship is still going strong. I just love how these two are each other's best allies, confidantes, and of course, their smoking hot er, 'interactions' (well as hot as can be for a YA novel without getting into anything too graphic).

Speaking of Sergei, something that surprised me in a good way was something that didn't happen in this book. Given how forceful Catherine was in declaring to him that as long as he lived, she would not love nor bed another, I felt for sure Sergei wouldn't live to the end of the book. Catherine's pronouncements read to me as extremely anvilicious, so it was a nice surprise that he was still alive (and as tight as ever with Catherine) by novel's end.

I cannot wait to read the third and final novel. I have faith Sherry Ficklin will do the end of the series justice.

0 of 0 people found the following review helpful.
Dying to read book 3!
By Connie Reichold
Book #2 has all of the intrigue, history, and romance that I loved about the first one. Things were a little different this time around though. Peter's wrath gets more intense and there's some pretty dark stuff that readers will have to deal with. The story takes you back and forth between two castles and courts. I was surprised to find out I didn't want to leave Winter Palace as much. After reading the first book, it kind of felt like home.

There is great character development for our dear little Sophie. After the heartbreaking events in Queen of Someday, she is certainly hardened. She has a lot of tough decisions to make and there isn't always a "right one". After she is finally pushed to her breaking point, she resolves to do something I don't think anyone saw coming.

Ficklin's story telling is beautiful and brilliant, as always, and I didn't want this book to end. I think the only real problem I have with these books is that they're too short! I'm definitely getting the conclusion, Queen of Always, soon, so catch up to me and watch out for the review!

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Minggu, 06 Maret 2011

[S442.Ebook] PDF Ebook Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried

PDF Ebook Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried

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Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried

Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried



Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried

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Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, by Thomas Seyfried

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention.�It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism.� However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited.� This book aims to provide�evidence, through case studies,�that cancer is primarily a metabolic disease requring�metabolic solutions for�its management and prevention.� Support for this position is�derived from critical assessment of current cancer theories.� Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the�same�cellular mutations that they demonstrate.

  • Sales Rank: #60704 in Books
  • Published on: 2012-06-26
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.60" h x 1.22" w x 6.30" l, 1.70 pounds
  • Binding: Hardcover
  • 438 pages

Review

“This book offers a refreshing perspective for anyone wanting to get a comprehensive background on the newer emerging interest in targeting cancer metabolism for therapy.”� (Doody’s, 11 January 2013)

“For the first time, an entire issue is being devoted to a review article based on a recent medical book. This is a departure from our usual format, but I think you will agree that this topic warrants the detailed treatment we have given it . . .This book should be required reading for all scientifically literate people who are involved in the cancer problem.”� (Advances in Cancer Treatment, 1 October 2012)

From the Back Cover

A groundbreaking new approach to understanding, preventing, and treating cancer

Supported by evidence from more than 1,000 scientific and clinical studies, this groundbreaking book demonstrates that cancer is a metabolic disease and, more importantly, that it can be more effectively managed and prevented when it is recognized as such. Moreover, the book provides detailed evidence that the traditional view of cancer as a genetic disease has been largely responsible for the failure to develop effective therapies and preventive strategies.

Cancer as a Metabolic Disease reevaluates the origins of cancer based on the latest research findings as well as several decades of studies exploring the defects in tumor cell energy metabolism. Author Thomas Seyfried is a biochemical geneticist who has been investigating the lipid biochemistry of cancer for thirty years. In this book, he carefully establishes why approaching cancer as a metabolic disease leads to better understanding and management of all aspects of the disease, including inflammation, vascularization, cell death, drug resistance, and genomic instability. In addition, the book explores:

  • Origin of metastasis
  • New treatment strategies that target tumor cell energy metabolism, including the ketogenic diet
  • More effective prevention strategies in light of the metabolic origin of cancer
  • Case studies and perspectives from the point of view of physicians, patients, and caregivers

Throughout the book, tables, figures, and graphs summarize key information and clarify complex concepts. In addition, the renowned cancer biochemist Peter Pedersen from Johns Hopkins Medical School also provides a historical perspective on the importance of the information presented in his foreward to the book.

Cancer as a Metabolic Disease is essential reading for all cancer researchers and clinicians as well as public health professionals. By treating cancer as a metabolic disease, the book sets readers on a new, more promising path to understanding the origins of cancer and developing new, more effective strategies to treat and prevent it.

About the Author

THOMAS N. SEYFRIED, PhD, has taught and conducted research in the fields of neurogenetics, neurochemistry, and cancer for more than twenty-five years at Yale University and Boston College. He has published more than 150 scientific articles and book chapters and is on the editorial boards of Nutrition & Metabolism, Journal of Lipid Research, Neurochemical Research, and ASN Neuro.

Most helpful customer reviews

259 of 263 people found the following review helpful.
Compelling evidence to support cancer as a metabolic disease
By Dominic D'Agostino
Dr. Seyfried provides compelling evidence that cancer is a metabolic disease (NOT a genetic disease), and this has major implications for the treatment and prevention of cancer.

According to Otto Warburg's theory of cancer, mitochondrial dysfunction is the origin of cancer. Dr. Seyfried has amassed extensive evidence to support Warburg's theory and advances the idea that cancer arises from defects in energy metabolism (mitochondrial dysfunction), and that this metabolic dysfunction triggers genomic instability, activates oncogenes and inactivating tumor suppressor genes. The author does an incredible job at convincing the reader that healthy mitochondria are the ultimate tumor suppressor.

It's clear that the strategy to treat cancer as a genetic disease is not working following metastasis of solid primary tumors, but this fuels the pharmaceutical industry. Enormous amounts of money are spent on large cancer genome projects, but this has not advanced our understanding or treatment of cancer as expected. The cancer genome project has actually created more confusion amongst cancer researchers, and this is very clear if one reads the literature. On the other hand, when cancer is viewed as a metabolic disease the strategies to treat and prevent cancer become incredibly simplistic and economical. For example, animals studies, case reports and anecdotal evidence demonstrate that metabolic therapies that lower blood glucose and elevate ketones will quickly reduce tumor growth, extend lifespan and in some cases cause complete remission. This strategy is effective because cancer cells are fueled by glucose and lack the ability to derive energy from ketones due to mitochondrial defects. Metabolic therapies exploit the mitochondrial defects associated with cancer by targeting glucose metabolism, reducing insulin and elevating ketones. These therapies are simple and include "therapeutic fasting", calorie restricted ketogenic diets and relatively cheap and safe drugs that target glycolysis, insulin and other cancer-specific metabolic pathways. The information in this book is valuable to patients and supported by extensive references. This book is technical (in parts), but the author has the ability to describe complicated processes with elegant simplicity.

I read this book immediately after reading "The Secret History of the War on Cancer" and "The Emperor of All Maladies". These are excellent books, but I found Dr. Seyfried's book to be more informative and empowering because it gives the reader clear evidence for the cause of cancer and highly effective strategies to prevent and treat the disease.

I would recommend this book to all cancer researchers, oncologists and layman interested in understanding the origin, management and treatment of cancer as a metabolic disease. This book will also be an extremely valuable resource for patients diagnosed with cancer.
Dominic D'Agostino, PhD, University of South Florida

203 of 206 people found the following review helpful.
The Most Important Book about Cancer Cell Metabolism
By Stephen Strum
I am a board-certified medical oncologist with 30 years experience in caring for cancer patients and another 20 years of research in cancer medicine dating back to 1963. Seyfried's "Cancer as a Metabolic Disease" is the most significant book I have read in my 50 years in this field. It should be required reading of all cancer specialists, physicians in general, scientific researchers in the field of cancer and for medical students. I cannot overstate what a valuable contribution Thomas Seyfried has made in writing this masterpiece.
Stephen B. Strum, MD, FACP
Medical Oncologist, Member of ASCO (American Society of Clinical Oncology) since 1975

118 of 122 people found the following review helpful.
a new look at caloric restriction and cancer
By GWY
It has been known for a long time that caloric restriction led to longevity but also that it stopped cancer growth, some completely and many partial suppression with later recurrences.

Dr. Seyfried spent his whole career looking at an old concept defining cancer as a metabolic abnormality (Warburg). The fact that our PET scans show high glucose uptake in almost all types of cancer proves that cancers have a unique metabolic abnormality unlike normal differentiated cells. Simply put cancer cells require large amounts of glucose, or sugar to survival and multiply.

The cancer cells have an inefficient metabolism utilizing fermentation or glycolysis instead of using mitochondria for a more efficient way of make ATP energy via oxidative phosphorylation.

Why our own medical profession has not looked into this feature of cancer for therapeutic strategies is also odd.
It is well know that Caloric Restriction stops cancer growth and many nutritional support such as macrobiotics and Hippocrates raw foods all have the common denominator of -- low calories with dense nutrition.

I suspect in the next 10 years there will be more discussions and research on use caloric restrictions, on use of alternative body fuel or energy source such as ketones, and glucose analogues, and ways to disrupt glycolysis and abnormal mitochondrial functions by using metabolic approaches to treat cancers.

I recommend this book to layman and professionals who are interested in the biology of cancers. top rating

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Jumat, 04 Maret 2011

[D153.Ebook] Ebook 22-Step Blueprint to Winning a Local Election, by Scott Meyer

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22-Step Blueprint to Winning a Local Election, by Scott Meyer

In 2015 with only $2,000, Scott Meyer used digital media and local campaign tactics to win a seat on city council and increase voter turnout 30%. The secrets of his surprise win are now available for you, and your community needs you to take action.

The health of our communities depends on the leadership of local politicians. The more voices that participate in the political process, the better our communities are. This blueprint shows how to run a successful, shoestring campaign, so anyone with an idea has an equal chance at winning an election.

Move your ideas into action with this actionable guide to running a successful campaign.

  • Sales Rank: #340111 in eBooks
  • Published on: 2016-02-12
  • Released on: 2016-02-12
  • Format: Kindle eBook

Most helpful customer reviews

1 of 1 people found the following review helpful.
Inbound your business like a city councilor
By Jenny Alvarez
Political elections are really just marketing campaigns. This eBook walks you through the similarities and explains how you can use election tactics to improve your business' marketing efforts, too. You'll leave this knowing what to focus your attention on, where to spend your precious budget, and most importantly, how to win your next campaign. There's nothing better than a how-do document that actually tells you how to do something, and this is one.

0 of 0 people found the following review helpful.
Helpful resource
By Becca Lingley
Excellent and succinct strategy - immediately applicable. Thank you for sharing your plan of action including time and cost elements.

0 of 0 people found the following review helpful.
It was ok
By John George
Nothing to spectacular here. Nailed the key concepts of Facebook ads being so important. 150 signs must of cost some $

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